Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604346 | 0.90 | HTT (0.42) | HTTTSHRMAPTLMNAHSP90AA1 | |
| SCHEMBL4551630 | 0.87 | GRM4 (0.43) | HTTTSHRSMN1; SMN2 | |
| SCHEMBL5593328 | 0.86 | RXFP1 (0.43) | HTTTSHRMAPTALDH1A1KMT2A | |
| SCHEMBL5602261 | 0.82 | HTT (0.43) | HTTTSHRMAPTLMNAHSP90AA1 | |
| SCHEMBL4407836 | 0.80 | NR1H4 (0.45) | HTTMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL5592971 | 0.79 | RXFP1 (0.42) | HTTTSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5592986 | 0.78 | RXFP1 (0.41) | HTTTSHRMAPTLMNASMN1; SMN2 | |
| SCHEMBL4414236 | 0.77 | NAMPT (0.43) | HTTTSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL5604188 | 0.77 | RAB9A (0.52) | TSHRLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5602348 | 0.76 | HTT (0.41) | HTTTSHRMAPTLMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |