SCHEMBL5602436

SCHEMBL5602436

CC1=c2ccccc2=C(C)[N]1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.39
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP1A2 P05177 2/20 0.33
NQO2 P16083 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
BACE1 P56817 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601432 0.77 L3MBTL1 (0.37) ACHETSHRLMNAALOX12L3MBTL1
SCHEMBL5601756 0.75 HSD11B1 (0.32) TSHRALDH1A1
SCHEMBL5601888 0.74
SCHEMBL5600004 0.73 CYP2A6 (0.36) ACHETSHRLMNACYP1A2ALDH1A1
Ethane SCHEMBL5905678 0.65 TSHR (0.43) ACHETSHRLMNAALOX12CYP1A2
SCHEMBL5602846 0.65 TSHR (0.32) ACHETSHRLMNAALOX12
SCHEMBL30702418 0.64 ALOX12 (0.46) ACHETSHRLMNAALOX12L3MBTL1
SCHEMBL29061457 0.64 ALOX12 (0.46) ACHETSHRLMNAALOX12L3MBTL1
SCHEMBL58153 0.64 ALOX12 (0.46) ACHETSHRLMNAALOX12L3MBTL1
SCHEMBL49871 0.64 ALOX12 (0.46) ACHETSHRLMNAALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed