Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602645 | 0.72 | HSD11B1 (0.38) | HSD11B1TSHRHTTTRPA1TRPM8 | |
| SCHEMBL1091995 | 0.72 | HSD11B1 (0.34) | HSD11B1TSHRALDH1A1 | |
| SCHEMBL5602458 | 0.66 | HSD11B1 (0.35) | HSD11B1TSHRHTTTRPA1TRPM8 | |
| SCHEMBL5602449 | 0.66 | HSD11B1 (0.40) | HSD11B1TSHRTRPA1TRPM8TRPV1 | |
| SCHEMBL24062 | 0.64 | MEN1 (0.37) | TSHRHTTALDH1A1 | |
| SCHEMBL5600573 | 0.63 | HSD11B1 (0.41) | HSD11B1MPL | |
| SCHEMBL28367426 | 0.63 | GPR3 (0.44) | HSD11B1TSHRMPLALDH1A1 | |
| SCHEMBL28372461 | 0.63 | GPR3 (0.49) | HSD11B1TSHRALDH1A1 | |
| SCHEMBL27860206 | 0.62 | MEN1 (0.35) | TSHRHTTALDH1A1 | |
| SCHEMBL27971780 | 0.62 | MEN1 (0.35) | TSHRHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |