Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | RAF1 | P04049 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412840 | 0.90 | RAF1 (0.51) | MAPK14RAF1BRAF | |
| SCHEMBL4551381 | 0.86 | RAB9A (0.53) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL4551703 | 0.85 | MAPK14 (0.48) | MAPK14RAF1BRAF | |
| SCHEMBL4552281 | 0.83 | RAF1 (0.45) | MAPK14RAF1BRAF | |
| SCHEMBL5603194 | 0.82 | RAF1 (0.43) | ALDH1A1MAPK14RAF1BRAF | |
| SCHEMBL4541474 | 0.82 | RAF1 (0.42) | KMT2AL3MBTL1KDM4EMAPK14RAF1 | |
| SCHEMBL4541525 | 0.82 | ACKR3 (0.44) | MAPK14RAF1BRAF | |
| SCHEMBL4551892 | 0.82 | RAF1 (0.44) | MAPK14RAF1BRAF | |
| SCHEMBL4411016 | 0.82 | BRAF (0.46) | RAB9AMAPK14RAF1BRAF | |
| SCHEMBL5604081 | 0.80 | RAF1 (0.42) | KDM4EMAPK14RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |