Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 6/20 | 0.42 |
| ▸ | BRAF | P15056 | 6/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551775 | 0.94 | MAPT (0.48) | RAF1BRAFMAPK14MAPTKDM4E | |
| SCHEMBL4409940 | 0.90 | RAF1 (0.53) | RAF1BRAFMAPK14 | |
| SCHEMBL4541474 | 0.89 | RAF1 (0.42) | RAF1BRAFMAPK14PLAUWDR5 | |
| SCHEMBL4551703 | 0.86 | MAPK14 (0.48) | RAF1BRAFMAPK14PLAUPOLB | |
| SCHEMBL5603996 | 0.86 | NAMPT (0.45) | RAF1BRAFMAPK14MAPT | |
| SCHEMBL4551565 | 0.86 | MAPT (0.39) | RAF1BRAFMAPK14PLAUMAPT | |
| SCHEMBL4552281 | 0.85 | RAF1 (0.45) | RAF1BRAFMAPK14PLAU | |
| SCHEMBL4551975 | 0.85 | L3MBTL1 (0.46) | MAPTKDM4EPOLB | |
| SCHEMBL4551605 | 0.84 | POLB (0.46) | RAF1BRAFMAPK14MAPTKDM4E | |
| SCHEMBL4551892 | 0.84 | RAF1 (0.44) | RAF1BRAFMAPK14PLAUEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |