Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL6851202 | 1.00 | — | — | |
| Guanidine SCHEMBL27473938 | 1.00 | — | — | |
| Guanidine SCHEMBL729040 | 0.96 | — | — | |
| Guanidine SCHEMBL27492536 | 0.96 | — | — | |
| Guanidine SCHEMBL56028 | 0.96 | — | — | |
| Guanidine SCHEMBL29044101 | 0.96 | TSHR (0.31) | — | |
| Guanidine SCHEMBL1903839 | 0.96 | TSHR (0.31) | — | |
| Guanidine SCHEMBL7755519 | 0.92 | — | — | |
| Guanidine SCHEMBL31206959 | 0.92 | — | — | |
| Guanidine SCHEMBL28453453 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048509-A1 | Diagnosis of invasive mold infection | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-03-03 | — | — | US | disclosed |
| US-20050009051-A1 | Diagnosis of mould infection | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS | 2005-01-13 | — | — | US | disclosed |
| WO-2004029216-A2 | DIAGNOSIS OF INVASIVE MOLD INFECTION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-04-08 | — | — | WO | disclosed |