Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600813 | 0.97 | PTGS2 (0.38) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5600541 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5602364 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5602157 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5600592 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5600178 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5602559 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5602423 | 0.95 | PTGS2 (0.40) | NOS1NOS3NOS2PTGS2PTPN5 | |
| SCHEMBL5604154 | 0.93 | PDK2 (0.32) | NOS1NOS3NOS2PTGS2BCHE | |
| SCHEMBL5600454 | 0.77 | MAOA (0.35) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |