SCHEMBL5604154

SCHEMBL5604154

c1ccc2c(c1)[N]c1c-2cccc1C1CC1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.32
NOS1 P29475 3/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
CYP2D6 P10635 2/20 0.31
HTR2C P28335 2/20 0.31
PDK4 Q16654 1/20 0.31
CYP1A2 P05177 1/20 0.31
PTGS2 P35354 1/20 0.30
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
USP30 Q70CQ3 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600813 0.93 PTGS2 (0.38) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5602976 0.93 NOS1 (0.37) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5602423 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5602157 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5602364 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5600592 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5600178 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5602559 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5600541 0.91 PTGS2 (0.40) NOS1NOS3NOS2PTGS2BCHE
SCHEMBL5601895 0.75 MAOA (0.37) PDK2NOS1NOS3NOS2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed