Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5603113

C[n+]1ccc(Cc2ccccc2)cc1.[Cl-]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.57
SLC22A2 O15244 1/20 0.52
SLC22A1 O15245 1/20 0.52
SLC22A3 O75751 1/20 0.52
SLC6A4 P31645 1/20 0.52
CHAT P28329 2/20 0.46
TP53 P04637 1/20 0.46
LTA4H P09960 2/20 0.45
LMNA P02545 3/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 1/20 0.45
APOBEC3A P31941 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10256785 0.98 CALM1 (0.60) CALM1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL14596514 0.87 HDAC8 (0.48) CALM1SLC22A2SLC22A1SLC22A3SLC6A4
Hydrochloric Acid SCHEMBL5604222 0.82 CALM1 (0.52) CALM1SLC22A2SLC22A1SLC22A3SLC6A4
Hydrochloric Acid SCHEMBL4811336 0.80 CALM1 (0.63) CALM1SLC22A2TP53LTA4HLMNA
SCHEMBL10257257 0.79 HTR2A (0.56) SLC22A2SLC22A1SLC22A3SLC6A4SMN1; SMN2
SCHEMBL10257260 0.79 CALM1 (0.55) CALM1SLC22A2SLC22A1SLC22A3SLC6A4
Diphenylmethane SCHEMBL27450549 0.76 CALM1 (0.86) CALM1SLC22A2TP53LTA4HLMNA
Diphenylmethane SCHEMBL29700351 0.76 CALM1 (0.86) CALM1SLC22A2TP53LTA4HLMNA
Diphenylmethane SCHEMBL1303 0.76 CALM1 (1.00) CALM1SLC22A2TP53LTA4HLMNA
Diphenylmethane SCHEMBL3792579 0.76 CALM1 (1.00) CALM1SLC22A2TP53LTA4HLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270602-B1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU KOSAN CO (JP) 2007-10-03 EP disclosed
US-7176266-B2 Catalyst for vinyl compound polymerization and process for producing vinyl polymer IDEMITSU KOSAN CO. LTD. (JP) 2007-02-13 US disclosed
US-6835788-B2 As polymerization catalyst IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
US-20040259720-A1 Catalyst for vinyl compound polymerization and process for producing vinyl polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-23 US disclosed
US-20030027716-A1 Catalyst for vinyl compounds and process for production of vinyl polymers IDEMITSU KOSAN CO. LTD. (JP) 2003-02-06 US disclosed
EP-1270602-A1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1136122-A1 TRANSITION METAL CATALYSTS AND PROCESSES FOR PRODUCING $g(a)-OLEFIN AND VINYL COMPOUND POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-09-26 EP disclosed