Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5603113 | 0.80 | CALM1 (0.57) | CALM1LMNAALDH1A1SMN1; SMN2KDM4E | |
| Diphenylmethane SCHEMBL29700351 | 0.80 | CALM1 (0.86) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Diphenylmethane SCHEMBL28172316 | 0.80 | CALM1 (1.00) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Diphenylmethane SCHEMBL3792579 | 0.80 | CALM1 (1.00) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Diphenylmethane SCHEMBL4361124 | 0.80 | CALM1 (1.00) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Diphenylmethane SCHEMBL14763944 | 0.80 | CALM1 (1.00) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Diphenylmethane SCHEMBL1303 | 0.80 | CALM1 (1.00) | CALM1LMNAALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1250828 | 0.78 | ALDH1A1 (0.67) | CALM1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6317405 | 0.77 | CALM1 (0.60) | CALM1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10256785 | 0.77 | CALM1 (0.60) | CALM1LMNAALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7404915-B2 | Electromagnetic wave shielding material, method of manufacturing the same and electromagnetic wave shielding material for plasma display panel | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20070138441-A1 | Electromagnetic wave shielding material, method of manufacturing the same and electromagnetic wave shielding material for plasma display panel | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070015094-A1 | ELECTROMAGNETIC WAVE SHIELDING MATERIAL, METHOD FOR MANUFACTURING THE SAME AND ELECTROMAGNETIC WAVE SHIELDING MATERIAL FOR PLASMA DISPLAY PANEL | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-01-18 | — | — | US | disclosed |