Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529821 | 0.84 | TRPV1 (0.43) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL1121836 | 0.83 | NOTUM (0.35) | CNR2DAGLATSHRL3MBTL1 | |
| SCHEMBL18982574 | 0.81 | NOTUM (0.34) | — | |
| SCHEMBL653830 | 0.81 | CYP11B1 (0.33) | TSHRRAB9AL3MBTL1 | |
| SCHEMBL752388 | 0.81 | POLB (0.33) | TRPV1CNR2CNR1DAGLATSHR | |
| SCHEMBL4400123 | 0.81 | CNR2 (0.44) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4408980 | 0.81 | HDAC6 (0.44) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4411347 | 0.81 | TRPV1 (0.47) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL6046474 | 0.81 | KDM4E (0.35) | TRPV1CNR2CNR1 | |
| SCHEMBL3141812 | 0.80 | HSPA5 (0.42) | CNR2MGLLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4683912-A1 | SUBSTITUTED THIOPHENE FUSED CYCLOHEXANONE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND THEIR USE AS PHARMACEUTICALS | Neurasic Therapeutics Inc. (CA) | 2026-01-28 | — | — | EP | disclosed |
| WO-2025035205-A1 | PHARMACEUTICAL COMBINATIONS COMPRISING A SUBSTITUTED THIOPHENE FUSED CYCLOHEXANONE DERIVATIVE AND A CYCLOOXYGENASE (COX) INHIBITOR, AND THEIR USE FOR THE TREATMENT OF PAIN | NEURASIC THERAPEUTICS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024192520-A1 | SUBSTITUTED THIOPHENE FUSED CYCLOHEXANONE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND THEIR USE AS PHARMACEUTICALS | NEURASIC THERAPEUTICS INC. (CA) | 2024-09-26 | — | — | WO | disclosed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2007124544-A1 | INTEGRASE INHIBITORS - 1 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | TRPV1 4674/4885CNR2 3297/4885CNR1 3005/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | TRPV1 4674/4885CNR2 3297/4885CNR1 3005/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | TRPV1 4674/4885CNR2 3297/4885CNR1 3005/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | TRPV1 4674/4885CNR2 3297/4885CNR1 3005/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | TRPV1 4674/4885CNR2 3297/4885CNR1 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.