Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603997 | 0.99 | CETP (0.32) | CETPSIRT2SIGMAR1HSD11B1HSD11B2 | |
| SCHEMBL5603288 | 0.95 | CETP (0.32) | CETPSIGMAR1OPRM1OPRL1 | |
| SCHEMBL5600959 | 0.89 | — | — | |
| SCHEMBL5601387 | 0.84 | — | — | |
| SCHEMBL5602361 | 0.74 | OPRM1 (0.33) | CETPSIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL5603449 | 0.73 | IDO1 (0.30) | — | |
| SCHEMBL5600498 | 0.72 | HSD11B1 (0.32) | OPRM1OPRD1OPRK1OPRL1CYP19A1 | |
| SCHEMBL28548755 | 0.68 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL28549243 | 0.68 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL28543963 | 0.68 | SIGMAR1 (0.56) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |