Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.65 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | GGT1 | P19440 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699559 | 0.90 | KDM4E (0.73) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL25398 | 0.87 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL30590970 | 0.87 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL2473332 | 0.87 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL4737527 | 0.87 | ALDH1A1 (0.69) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL11791031 | 0.86 | KDM4E (0.65) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL22972824 | 0.86 | KDM4E (0.73) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL25303461 | 0.85 | KDM4E (0.97) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL27414704 | 0.85 | KDM4E (0.67) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL11799149 | 0.84 | KDM4E (0.65) | KDM4EHSD17B10LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183269-B2 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2007-02-27 | — | — | US | disclosed |
| US-20040147493-A1 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2004-07-29 | — | — | US | disclosed |
| US-6727235-B2 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030166621-A1 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2003-09-04 | — | — | US | disclosed |
| US-6525038-B1 | Synergistic composition of 5-(2,4-difluorophenyl) salicylic acid and 2-hydroxy-4-aminobenzoic acid | KREUTZ WERNER (DE) | 2003-02-25 | — | — | US | disclosed |
| US-6395720-B1 | ANTICANCER AGENTS | KREUTZ WERNER (DE) | 2002-05-28 | — | — | US | disclosed |