Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.62 |
| ▸ | GGT1 | P19440 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CFD | P00746 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspirin SCHEMBL22972824 | 0.93 | KDM4E (0.73) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL5604181 | 0.90 | KDM4E (0.76) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL31618292 | 0.88 | CFD (0.69) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL138320 | 0.88 | CFD (0.69) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Methoxymethane SCHEMBL5317565 | 0.85 | CFD (0.65) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL30590970 | 0.85 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL25398 | 0.85 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL2473332 | 0.85 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL25303461 | 0.84 | KDM4E (0.97) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL2467028 | 0.83 | KDM4E (0.67) | KDM4EHSD17B10LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022114-A1 | A METHOD FOR PROMOTING TISSUE REPAIR | DUMEX-ALPHARMA A/S (DK) | 1998-05-28 | — | — | WO | disclosed |