Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.86 |
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | ESR1 | P03372 | 1/20 | 0.86 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.86 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.86 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.86 |
| ▸ | GGT1 | P19440 | 1/20 | 0.86 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.86 |
| ▸ | BLM | P54132 | 1/20 | 0.86 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diplosalsalate SCHEMBL30590970 | 1.00 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL2473332 | 1.00 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Diplosalsalate SCHEMBL25303461 | 0.98 | KDM4E (0.97) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL29350479 | 0.93 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL10456693 | 0.93 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL1331740 | 0.93 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL7580 | 0.93 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL1353 | 0.93 | KDM4E (1.00) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL20484785 | 0.91 | KDM4E (0.96) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| Aspirin SCHEMBL21488922 | 0.91 | KDM4E (0.96) | KDM4EHSD17B10LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307283-A1 | COMPOSITIONS AND METHODS FOR DECREASING PIGMENTATION | THE GENERAL HOSPITAL CORPORATION | 2024-09-19 | — | — | US | claimed |
| CN-118340907-A | Polymer conjugates comprising bioactive agents | 波利艾克蒂瓦有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118215461-A | Compositions and methods for reducing pigmentation | 总医院公司 | 2024-06-18 | — | — | CN | claimed |
| EP-4366837-A2 | COMPOSITSONS AND METHODS FOR DECREASING PIGMENTATION | The General Hospital Corporation (US) | 2024-05-15 | — | — | EP | claimed |
| US-20230285282-A1 | OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT | OCULAR THERAPEUTIX INC (US) | 2023-09-14 | — | — | US | claimed |
| EP-4236943-A1 | OCULAR IMPLANT CONTAINING AN ACTIVE AGENT | Ocular Therapeutix, Inc. (US) | 2023-09-06 | — | — | EP | claimed |
| WO-2023283554-A2 | COMPOSITSONS AND METHODS FOR DECREASING PIGMENTATION | THE GENERAL HOSPITAL CORPORATION (US) | 2023-01-12 | — | — | WO | claimed |
| CN-115247192-A | Enzymatic preparation technology of acyl/aroyl coenzyme A | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | claimed |
| WO-2022093818-A1 | OCULAR IMPLANT CONTAINING AN ACTIVE AGENT | OCULAR THERAPEUTIX, INC. (US) | 2022-05-05 | — | — | WO | claimed |
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | POLYACTIVA PTY LTD (AU) | 2020-09-01 | — | — | US | claimed |
| EP-0759899-B1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX SA (FR) | 1999-09-15 | — | — | EP | claimed |
| EP-0931065-A2 | NITRIC ESTER DERIVATIVES AND THEIR USE IN URINARY INCONTINENCE AND OTHER DISEASES | NICOX S.A. (FR) | 1999-07-28 | — | — | EP | claimed |
| WO-1998022114-A1 | A METHOD FOR PROMOTING TISSUE REPAIR | DUMEX-ALPHARMA A/S (DK) | 1998-05-28 | — | — | WO | claimed |
| WO-1998009948-A2 | NITRIC ESTER DERIVATIVES AND THEIR USE IN URINARY INCONTINENCE AND OTHER DISEASES | NICOX S.A. (FR) | 1998-03-12 | — | — | WO | claimed |
| US-5635443-A | IMMERSING THE STEM OF CUT FLOWER IN A SOLUTION CONTAINING SURFACTANT, FRAGRANCE, SOLVENT, WATER, ACETYLSALICYLIC ACID OR ACETYLSALICYLICSALICYLIC ACID OR BOTH, SODIUM CHLORIDE, SODIUM BICARBONATE, PLANT FOOD AND HORMONE AND ANTIFOAM AGENT | FLORASYNTH, INC. (US) | 1997-06-03 | — | — | US | claimed |
| EP-0759899-A1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX S.A. (FR) | 1997-03-05 | — | — | EP | claimed |
| WO-1995030641-A1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX S.A. (FR) | 1995-11-16 | — | — | WO | claimed |
| US-4287174-A | CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID | THE PROCTOR & GAMBLE COMPANY (US) | 1981-09-01 | — | — | US | claimed |
| US-4275059-A | IN COMBINATION WITH A DIPHOSPHONATE COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| EP-0004686-A2 | Anti-ulcer composition | THE PROCTER & GAMBLE COMPANY (US) | 1979-10-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | MSN, PAM, PARG | KDM4E 3935/4885HSD17B10 3174/4885LMNA 1925/4885 |
| US-20230285282-A1 | OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT | ERBB2, BTK, ERBB3 | KDM4E 1064/4885HSD17B10 2167/4885LMNA 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.