Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.47 |
| ▸ | RAF1 | P04049 | 12/20 | 0.47 |
| ▸ | CSF1R | P07333 | 4/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604230 | 0.90 | RAF1 (0.59) | BRAFRAF1CSF1RLYN | |
| SCHEMBL4552240 | 0.87 | RAF1 (0.50) | BRAFRAF1CSF1R | |
| SCHEMBL5603594 | 0.85 | CSF1R (0.48) | BRAFRAF1CSF1R | |
| SCHEMBL5593491 | 0.79 | RAF1 (0.60) | BRAFRAF1CSF1R | |
| SCHEMBL4411100 | 0.79 | RAF1 (0.58) | BRAFRAF1CSF1RLYN | |
| SCHEMBL4552281 | 0.79 | RAF1 (0.45) | BRAFRAF1CSF1R | |
| SCHEMBL4418487 | 0.79 | MAPK14 (0.48) | BRAFRAF1CSF1R | |
| SCHEMBL4551381 | 0.78 | RAB9A (0.53) | BRAFRAF1 | |
| SCHEMBL5602744 | 0.77 | RAB9A (0.43) | BRAFRAF1 | |
| SCHEMBL4551703 | 0.77 | MAPK14 (0.48) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |