SCHEMBL5604240

SCHEMBL5604240

Cc1cc(-c2cc(C)c(Oc3cccc(N)c3)c(C)c2)cc(C)c1Oc1cccc(N)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
POLB P06746 1/20 0.58
HSP90AA1 P07900 1/20 0.58
MAOB P27338 2/20 0.55
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 3/20 0.52
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
GAA P10253 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MITF O75030 1/20 0.42
GFER P55789 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42
ATM Q13315 1/20 0.41
TSHR P16473 1/20 0.41
MAP4K4 O95819 1/20 0.41
CASP1 P29466 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935263 0.92 MAOB (0.56) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL31180032 0.89 MAOB (0.60) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL6934775 0.84 MAPT (0.53) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL2993851 0.82 ALDH1A1 (0.52) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL9082819 0.82 MAPT (0.50) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL31179977 0.81 MAPT (0.53) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL8961346 0.80 MAPT (0.49) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL9081581 0.80 MAPT (0.49) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL9770081 0.79 MAOB (0.49) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL10476967 0.79 MAPT (0.54) MAPTPOLBHSP90AA1MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4103630-A None JP disclosed
JP-4183721-A None JP disclosed
JP-63186735-A None JP disclosed
JP-63126848-A None JP disclosed
US-9735429-B2 Lithium ion secondary battery HITACHI, LTD. (JP) 2017-08-15 US disclosed
EP-2858150-B1 LITHIUM ION SECONDARY BATTERY HITACHI LTD (JP) 2017-03-15 EP disclosed
EP-2899231-A1 Aerospace articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899232-A1 Oil and gas recovery articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899230-A1 Automotive articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899233-A1 Chemical processing articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
US-5013817-A Monoamine reactant, melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0384712-A2 Carbon-fiber-reinforced polyimide resin compositions MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-29 EP disclosed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 US disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed
EP-0292243-A2 Heat resistant resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-11-23 EP disclosed
JP-S63186735-A POLYIMIDE AND HEAT-RESISTANT ADHESIVE COMPRISING SAME MITSUI TOATSU CHEM INC 1988-08-02 JP disclosed
JP-S63126848-A 4,4'-BIS(3-AMINOPHENOXY)-3,3',5,5'-TETRAMETHYLBIPHENYL AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1988-05-30 JP disclosed