Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578456 | 0.83 | ALDH1A1 (0.46) | MAPTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL8961374 | 0.82 | CYP3A4 (0.45) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL8364512 | 0.81 | MAOB (0.56) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL31180032 | 0.80 | MAOB (0.60) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL5604240 | 0.80 | MAPT (0.58) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL3151082 | 0.80 | MAOB (0.59) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL9770081 | 0.78 | MAOB (0.49) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL6934775 | 0.76 | MAPT (0.53) | MAPTPOLBHSP90AA1CYP3A4TP53 | |
| SCHEMBL21496115 | 0.76 | ALDH1A1 (0.48) | MAPTTP53TSHRALDH1A1FFAR1 | |
| SCHEMBL2993851 | 0.75 | ALDH1A1 (0.52) | MAPTPOLBHSP90AA1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514748-A | POLYMER FOR SLIDING CONTAINING PHENOLIC RESINS AND LUBRICANTS WITH POLYIMIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-05-07 | — | — | US | disclosed |