SCHEMBL6934775

SCHEMBL6934775

Cc1cc(C(C)(C)c2cc(C)c(Oc3cccc(N)c3)c(C)c2)cc(C)c1Oc1cccc(N)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
POLB P06746 1/20 0.53
HSP90AA1 P07900 1/20 0.53
MAOB P27338 2/20 0.50
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 3/20 0.47
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MITF O75030 1/20 0.39
GFER P55789 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39
ATM Q13315 1/20 0.39
TSHR P16473 1/20 0.38
F10 P00742 1/20 0.36
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9082819 0.97 MAPT (0.50) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL9081581 0.95 MAPT (0.49) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL6935311 0.93 MAOB (0.51) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL31180032 0.84 MAOB (0.60) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL5604240 0.84 MAPT (0.58) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL10409619 0.81 MAPT (0.47) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL1854909 0.81 ALDH1A1 (0.53) MAPTPOLBMAOBALDH1A1CYP3A4
SCHEMBL310896 0.81 MAOB (0.60) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL29436307 0.81 MAOB (0.60) MAPTPOLBHSP90AA1MAOBALDH1A1
SCHEMBL6933749 0.81 MAOB (0.47) MAPTPOLBHSP90AA1MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62148455-A None JP disclosed
US-6575859-B2 A belt tension adjusting device comprising a stationary fulcrum shaft, an arm pivotally supported on said fulcrum shaft through a slide bearing formed of a synthetic resin, a tension pulley mounted on said arm at one end thereof for NTN CORPORATION (JP) 2003-06-10 US disclosed
US-6513986-B2 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2003-02-04 US disclosed
US-20010021679-A1 Belt tension adjusting device NTN CORPORATION (JP) 2001-09-13 US disclosed
US-20010014545-A1 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2001-08-16 US disclosed
US-5900453-A BLEND OF POLYIMIDE, POLYTETRAFLUOROETHYLENE AND AROMATIC POLYESTER NTN CORPORATION (JP) 1999-05-04 US disclosed
EP-0633294-B1 Polyimide based resin composition MITSUI CHEMICALS INC (JP) 1998-06-10 EP disclosed
US-5726232-A TETRAFLUOROETHYLENE POLYMER, LITHIUM PHOSPHATE NTN CORPORATION (JP) 1998-03-10 US disclosed
EP-0591551-B1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1998-03-04 EP disclosed
EP-0812885-A2 Polyimide based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-12-17 EP disclosed
EP-0384712-A2 Carbon-fiber-reinforced polyimide resin compositions MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-29 EP disclosed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 US disclosed
EP-0368590-A2 Production process for polyimide fibers MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-16 EP disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed
EP-0292243-A2 Heat resistant resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-11-23 EP disclosed
EP-0253891-A1 AROMATIC BISMALEIMIDO COMPOUNDS AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-01-27 EP disclosed
JP-S62148455-A METHYL-SUBSTITUTED COMPOUND OF 2,2-BIS(4-(3-AMINOPHENOXY) PHENYL)PROPANE AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1987-07-02 JP disclosed
EP-0192480-A1 Bis(3-aminophenoxy) aromatics and method of preparing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-08-27 EP disclosed