SCHEMBL5604280

SCHEMBL5604280

CCCCCCCCCCCCCCOCC(O)CN(CCO)C(=O)CCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.53
LPAR5 Q9H1C0 1/20 0.49
HTT P42858 2/20 0.48
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
PLA2G2C Q5R387 3/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SPHK1 Q9NYA1 1/20 0.41
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.39
MAPT P10636 1/20 0.39
P2RY10 O00398 1/20 0.39
LPAR1 Q92633 2/20 0.39
LPAR3 Q9UBY5 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498430 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL8536163 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL10601287 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL5180047 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL5178380 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL5179103 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL9417254 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL5180698 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL2497008 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4
SCHEMBL9351933 1.00 USP2 (0.53) USP2LPAR5HTTCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3101407-B1 KIT AND METHOD FOR ELECTRON MICROSCOPE OBSERVATION JAPAN SCIENCE & TECH AGENCY (JP) 2023-03-08 EP disclosed
EP-1031348-B1 Interleukin-4 production inhibitors KAO CORP (JP) 2007-07-25 EP disclosed
US-6974596-B2 Interleukin-4 production inhibitors KAO CORPORATION (JP) 2005-12-13 US disclosed
US-6960359-B2 Interleukin-4 production inhibitors KAO CORPORATION (JP) 2005-11-01 US disclosed
EP-0965327-B1 WRINKLING MODIFIERS KAO CORP (JP) 2005-03-16 EP disclosed
US-20030129265-A1 Interleukin-4 production inhibitors KAO CORPORATION (JP) 2003-07-10 US disclosed
US-20030129266-A1 Comprising cedrol, cedrenol, farnesol, patchouli alcohol or vetiverol; antiallergic agents and atopic dermatitis preventives KAO CORPORATION (JP) 2003-07-10 US disclosed
US-6495171-B2 BATH MEDICINE; ANTIALLERGENS, SKIN DISORDERS KAO CORPORATION (JP) 2002-12-17 US disclosed
EP-0808625-B1 External skin-care composition KAO CORP (JP) 2002-08-07 EP disclosed
US-20010031285-A1 Interleukin-4 production inhibitors KAO CORPORATION (JP) 2001-10-18 US disclosed
EP-1031348-A2 Interleukin-4 production inhibitors Kao Corporation (JP) 2000-08-30 EP disclosed
EP-0965327-A1 WRINKLING MODIFIERS Kao Corporation (JP) 1999-12-22 EP disclosed
EP-0808625-A1 External skin-care composition Kao Corporation (JP) 1997-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129265-A1 Interleukin-4 production inhibitors IL4, IL33, IL36G USP2 3647/4885LPAR5 1747/4885HTT 4551/4885
US-20010031285-A1 Interleukin-4 production inhibitors IL4, IL33, IL36G USP2 3647/4885LPAR5 1747/4885HTT 4551/4885
US-20030129266-A1 Comprising cedrol, cedrenol, farnesol, patchouli alcohol or vetiverol; antiallergic agents and atopic dermatitis preventives IL4, IL33, IL36G USP2 3608/4885LPAR5 1311/4885HTT 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.