Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7762679 | 0.93 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7759995 | 0.88 | NPC1 (0.30) | ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2525067 | 0.84 | CA12 (0.36) | ALDH1A1HPGDMAPK1L3MBTL1NISCH | |
| Hydrochloric Acid SCHEMBL29612287 | 0.84 | CA12 (0.36) | ALDH1A1HPGDMAPK1L3MBTL1NISCH | |
| Hydrochloric Acid SCHEMBL3680021 | 0.83 | MAOA (0.38) | CYP1A2 | |
| Fluoride Ion SCHEMBL7639237 | 0.81 | CA12 (0.36) | ALDH1A1HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8674061 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6553574 | 0.79 | PDCD1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL17698617 | 0.78 | CA12 (0.33) | ALDH1A1HPGDMAPK1L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2522861 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160949-B2 | Olefin block copolymers, processes for producing the same and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20030055179-A1 | Olefin block copolymers processes for producing the same and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2003-03-20 | — | — | US | disclosed |