Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593028 | 0.78 | GAA (0.48) | BRAFPLA2G7RAF1RAB9ASMN1; SMN2 | |
| SCHEMBL5604301 | 0.74 | POLB (0.45) | SMN1; SMN2MAPTHPGDCYP1A2CYP2C19 | |
| SCHEMBL3921413 | 0.71 | PLA2G7 (0.37) | PLA2G7RAF1CYP3A4CASP1TSHR | |
| SCHEMBL4204404 | 0.70 | HCAR2 (0.50) | RAB9ASMN1; SMN2MEN1NPC1KMT2A | |
| SCHEMBL18147661 | 0.69 | CASP1 (0.44) | SMN1; SMN2MAPTHPGDMEN1NPC1 | |
| SCHEMBL3606930 | 0.68 | CYP2A6 (0.49) | BRAFUCHL1USP30RAB9ASMN1; SMN2 | |
| SCHEMBL1018391 | 0.66 | PDE10A (0.44) | MAPTHPGDMEN1NPC1CYP1A2 | |
| SCHEMBL30092397 | 0.63 | PLA2G7 (0.65) | PLA2G7RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL31607621 | 0.63 | PLA2G7 (0.65) | PLA2G7RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL8848693 | 0.63 | PLA2G7 (0.65) | PLA2G7RAB9ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |