Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.43 |
| ▸ | RAF1 | P04049 | 11/20 | 0.42 |
| ▸ | BRAF | P15056 | 11/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417882 | 0.87 | MAPK14 (0.59) | MAPK14RAF1BRAFHSPB1LYN | |
| SCHEMBL4413422 | 0.86 | MAPK14 (0.59) | MAPK14RAF1BRAFHSPB1LYN | |
| SCHEMBL5601764 | 0.83 | BRAF (0.40) | RAF1BRAF | |
| SCHEMBL4420764 | 0.81 | BRAF (0.61) | MAPK14RAF1BRAFHSPB1 | |
| SCHEMBL4551380 | 0.78 | BRAF (0.46) | RAF1BRAF | |
| SCHEMBL4417865 | 0.76 | BRAF (0.47) | MAPK14RAF1BRAF | |
| SCHEMBL4410286 | 0.76 | RAF1 (0.49) | MAPK14RAF1BRAF | |
| SCHEMBL4410231 | 0.75 | BRAF (0.48) | MAPK14RAF1BRAF | |
| SCHEMBL14473010 | 0.75 | RAF1 (0.45) | MAPK14RAF1BRAF | |
| SCHEMBL5593431 | 0.75 | RAF1 (0.49) | MAPK14RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |