Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031699 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL4334899 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL20606290 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL21829 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL246612 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL13048767 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL1401943 | 0.94 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL8333968 | 0.93 | TDP1 (0.58) | TDP1LMNAALDH1A1TSHRNPC1 | |
| SCHEMBL29369518 | 0.93 | ALDH1A1 (0.68) | LMNAALDH1A1TSHRNPC1MAPT | |
| SCHEMBL29662808 | 0.93 | ALDH1A1 (0.68) | LMNAALDH1A1TSHRNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314021-B2 | Formulations containing insect repellent compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140288167-A1 | Formulations Containing Insect Repellent Compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-25 | — | — | US | disclosed |
| US-8771718-B2 | Formulated tick and insect repellent compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-08 | — | — | US | disclosed |
| US-8748477-B2 | Formulations containing insect repellent compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-10 | — | — | US | disclosed |
| US-20070264297-A1 | Formulated tick and insect repellent compositions | 1,4Group, Inc. | 2007-11-15 | — | — | US | disclosed |
| US-20060223878-A1 | Formulations containing insect repellent compounds | 1,4Group, Inc. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288167-A1 | Formulations Containing Insect Repellent Compounds | CAT, HNMT, MME | TDP1 3118/4885LMNA 3157/4885ALDH1A1 1079/4885 |
| US-20060223878-A1 | Formulations containing insect repellent compounds | CAT, HNMT, MME | TDP1 3118/4885LMNA 3157/4885ALDH1A1 1079/4885 |
| US-20070264297-A1 | Formulated tick and insect repellent compositions | MME, FNTA, ACHE | TDP1 3003/4885LMNA 1412/4885ALDH1A1 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.