Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443383 | 0.96 | FAAH (0.38) | FAAHTDP1DGAT1CYP2D6EPHX2 | |
| SCHEMBL2648388 | 0.85 | DGAT1 (0.42) | TDP1DGAT1CYP2D6EPHX2GAA | |
| SCHEMBL10379839 | 0.83 | DGAT1 (0.34) | FAAHTDP1DGAT1CYP2D6EPHX2 | |
| SCHEMBL5691337 | 0.82 | GAA (0.42) | TDP1DGAT1CYP2D6EPHX2GAA | |
| SCHEMBL140252 | 0.80 | — | — | |
| SCHEMBL241533 | 0.80 | DGAT1 (0.46) | TDP1DGAT1CYP2D6GAAMEN1 | |
| SCHEMBL28792442 | 0.79 | EPHX2 (0.35) | TDP1DGAT1CYP2D6EPHX2GAA | |
| SCHEMBL182237 | 0.79 | TDP1 (0.41) | TDP1DGAT1CYP2D6EPHX2GAA | |
| SCHEMBL10833684 | 0.79 | TDP1 (0.38) | TDP1DGAT1CYP2D6EPHX2GAA | |
| SCHEMBL12539245 | 0.78 | TDP1 (0.36) | FAAHTDP1DGAT1CYP2D6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | claimed |
| EP-0208662-B1 | PROCESS FOR MANUFACTURING R(-)-NORCARNITINE TERT-BUTYL ESTER | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-12-14 | — | — | EP | claimed |
| JP-61010569-A | — | — | None | — | — | JP | disclosed |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024190386-A1 | RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, POLYMER, AND COMPOUND | JSR株式会社 | 2024-09-19 | — | — | WO | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| CN-113512008-A | Continuous refining method of anhydrous Mica acid | 上海应用技术大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-109574830-B | Rosuvastatin calcium intermediate, and preparation method and application thereof | 浙江宏元药业股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| US-10961515-B1 | Carbonyl reductase variant and its use in preparation of (R)-4-chloro-3-hydroxybutyrate | FUDAN UNIVERSITY (CN) | 2021-03-30 | — | — | US | disclosed |
| EP-0208662-B1 | PROCESS FOR MANUFACTURING R(-)-NORCARNITINE TERT-BUTYL ESTER | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-12-14 | — | — | EP | disclosed |
| EP-0257275-A2 | Cephalosporin and penicillin derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |
| EP-0233228-A1 | PHARMACEUTICALLY ACTIVE 2-THIOMETHYL-SUBSTITUTED-1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987000836-A1 | PHARMACEUTICALLY ACTIVE 2-THIOMETHYL-SUBSTITUTED-1,4-DIHYDROPYRIDINES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1987-02-12 | — | — | WO | disclosed |
| EP-0208662-A1 | Process for manufacturing r(-)-norcarnitine tert-butyl ester | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1987-01-14 | — | — | EP | disclosed |
| EP-0208662-A1 | Process for manufacturing r(-)-norcarnitine tert-butyl ester | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1987-01-14 | — | — | EP | disclosed |
| US-4616084-A | Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | disclosed |
| JP-S6110569-A | PREPARATION OF 2-(2-AMINOTHIAZOLE)-ACETIC ACID DERIVATIVE | SANKEI YAKUHIN KK | 1986-01-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BCL2A1, BAX | FAAH 3841/4885TDP1 2093/4885DGAT1 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.