SCHEMBL560450

SCHEMBL560450

COC(=O)/C=C\C(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ALDH1A1 P00352 4/20 0.40
HTT P42858 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TYR P14679 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MEN1 O00255 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560289 1.00 HCAR2 (0.41) HCAR2KEAP1NFE2L2ALDH1A1HTT
SCHEMBL560290 1.00 HCAR2 (0.41) HCAR2KEAP1NFE2L2ALDH1A1HTT
SCHEMBL5973442 0.94 HCAR2 (0.37) HCAR2ALDH1A1HTTMAPTKDM4E
SCHEMBL5974325 0.94 HCAR2 (0.37) HCAR2ALDH1A1HTTMAPTKDM4E
SCHEMBL5973451 0.94 HCAR2 (0.37) HCAR2ALDH1A1HTTMAPTKDM4E
SCHEMBL28219395 0.89 HCAR2 (0.44) HCAR2HTTMAPTKDM4ELMNA
SCHEMBL4647510 0.82 MAPT (0.37) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL2189980 0.81 THRB (0.38) ALDH1A1MAPTKMT2ATSHR
SCHEMBL2144573 0.80 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALDH1A1HTT
SCHEMBL2144442 0.80 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-4617318-A1 RESIN COMPOSITION AND MOLDED BODY MCPP Innovation LLC (JP) 2025-09-17 EP disclosed
US-20250257215-A1 RESIN COMPOSITION AND MOLDED ARTICLE MCPP INNOVATION LLC (JP) 2025-08-14 US disclosed
CN-109952328-B (Meth) acrylic copolymer, coating composition, coated article, and method for forming multilayer coating film 三菱化学株式会社 2025-01-14 CN disclosed
CN-118159603-A Resin composition, method for producing resin composition, molding material, and article 三菱化学株式会社 2024-06-07 CN disclosed
WO-2024101418-A1 RESIN COMPOSITION AND MOLDED BODY MCPPイノベーション合同会社 2024-05-16 WO disclosed
CN-116635488-A Compounds, polymers and antifouling coating compositions 三菱化学株式会社 2023-08-22 CN disclosed
US-11421065-B2 Adhesive resin composition and adhesive sheet MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-23 US disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
EP-0714957-B1 Hydrolyzable self-polishing coating composition NOF CORP (JP) 1998-03-04 EP disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed
EP-0646630-B1 Antifouling coating composition NOF CORP (JP) 1997-04-23 EP disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
US-5436284-A Preventing attachment of organisms to surfaces of structures submerged in seawater NOF CORPORATION (JP) 1995-07-25 US disclosed
EP-0646630-A1 Antifouling coating composition NOF CORPORATION (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 HCAR2 325/4885KEAP1 1681/4885NFE2L2 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.