Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613222 | 0.88 | ALOX5 (0.52) | GAAMAPTMAPK1LMNAVEGFA | |
| SCHEMBL5613221 | 0.88 | ALOX5 (0.52) | GAAMAPTMAPK1LMNAVEGFA | |
| SCHEMBL3100738 | 0.81 | GAA (0.56) | GAAMAPTMAPK1LMNATSHR | |
| SCHEMBL18021941 | 0.81 | VEGFA (0.48) | MAPTVEGFAEGLN1FAAHTSHR | |
| SCHEMBL3101191 | 0.80 | GAA (0.57) | GAAMAPTMAPK1LMNATSHR | |
| SCHEMBL9251960 | 0.79 | GAA (0.50) | GAAMAPTMAPK1LMNAFAAH | |
| SCHEMBL3103923 | 0.78 | GAA (0.53) | GAAMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL30809948 | 0.78 | VEGFA (0.48) | MAPTVEGFAEGLN1FGFR1KMT2A | |
| SCHEMBL24099834 | 0.77 | VEGFA (0.49) | GAAVEGFAEGLN1SMN1; SMN2KMT2A | |
| SCHEMBL3097222 | 0.77 | KDM4E (0.56) | GAAMAPTMAPK1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051314-A1 | CURCUMINOID COMPOUNDS FOR INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR-1 | AMERICAN DIAGNOSTICA INC. (US) | 2007-05-10 | — | — | WO | disclosed |