Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097253 | 0.93 | KDM4E (0.48) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL3100738 | 0.87 | GAA (0.56) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL3084472 | 0.86 | GAA (0.51) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL3101191 | 0.86 | GAA (0.57) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL3103923 | 0.84 | GAA (0.53) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL3094374 | 0.83 | GFER (0.45) | KDM4EGAAMAPTLMNAKMT2A | |
| SCHEMBL3080730 | 0.81 | ALDH1A1 (0.47) | KDM4EGAAMAPTLMNAKMT2A | |
| SCHEMBL4898052 | 0.78 | MAPK1 (0.56) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL9251960 | 0.78 | GAA (0.50) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL5604541 | 0.77 | GAA (0.49) | KDM4EGAAMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | claimed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | claimed |
| EP-2069022-A2 | AGENT FOR DYEING FIBERS COMPRISING KERATIN | Henkel AG & Co. KGaA (DE) | 2009-06-17 | — | — | EP | claimed |
| WO-2008074578-A2 | AGENT FOR DYEING FIBERS COMPRISING KERATIN | HENKEL AG & CO. KGAA (DE) | 2008-06-26 | — | — | WO | claimed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | disclosed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | disclosed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | disclosed |
| WO-2008074578-A2 | AGENT FOR DYEING FIBERS COMPRISING KERATIN | HENKEL AG & CO. KGAA (DE) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | KRT18, CRYAA, CKAP4 | KDM4E 1842/4885GAA 3583/4885MAPT 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.