Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100738 | 0.82 | GAA (0.56) | GAAMAPTMAPK1LMNATSHR | |
| SCHEMBL3101191 | 0.81 | GAA (0.57) | GAAMAPTMAPK1LMNATSHR | |
| SCHEMBL5604541 | 0.79 | GAA (0.49) | GAAMAPTMAPK1LMNAFAAH | |
| SCHEMBL3103923 | 0.79 | GAA (0.53) | GAAMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9249919 | 0.78 | GAA (0.61) | GAAMAPTMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL3097222 | 0.78 | KDM4E (0.56) | GAAMAPTMAPK1LMNAFAAH | |
| SCHEMBL9252788 | 0.78 | KMT2A (0.55) | MAPTMAPK1LMNAFAAHTSHR | |
| Hydrochloric Acid SCHEMBL9250695 | 0.77 | GAA (0.59) | GAAMAPTMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL4898052 | 0.76 | MAPK1 (0.56) | GAAMAPTMAPK1LMNATSHR | |
| SCHEMBL9256748 | 0.74 | CYP2C19 (0.49) | LMNATSHRSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |