Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849016 | 0.72 | ALDH1A1 (0.74) | ALDH1A1MAPK1MAPTKDM4EHPGD | |
| SCHEMBL1545990 | 0.69 | ALDH1A1 (0.75) | ALDH1A1MAPK1MAPTKDM4EHPGD | |
| SCHEMBL260676 | 0.69 | KDM4E (0.43) | ALDH1A1MAPK1MAPTKDM4EADORA2A | |
| SCHEMBL1546099 | 0.68 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EHPGDADORA2A | |
| SCHEMBL11606618 | 0.66 | ALDH1A1 (0.55) | ALDH1A1MAPK1HPGDADORA1CYP3A4 | |
| SCHEMBL21185866 | 0.65 | KDM4E (0.49) | ALDH1A1MAPK1MAPTKDM4EADORA2A | |
| SCHEMBL3193706 | 0.65 | POLB (0.43) | ALDH1A1MAPTKDM4EHPGDADORA2A | |
| SCHEMBL6804165 | 0.64 | ALDH1A1 (0.50) | ALDH1A1MAPK1MAPTKDM4EHPGD | |
| SCHEMBL10711246 | 0.64 | KDM4E (0.40) | ALDH1A1MAPK1MAPTKDM4EADORA2A | |
| SCHEMBL11690456 | 0.62 | KDM4E (0.39) | ALDH1A1MAPK1MAPTKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044968-B1 | 6-Amino-2-oxo-pyrimidin-4-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2007-04-18 | — | — | EP | disclosed |