Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394776 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL3875250 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL2760405 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL8174724 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL4763472 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL260676 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL13847007 | 0.69 | RAB9A (0.36) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL21886582 | 0.68 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL91340 | 0.68 | ALDH1A1 (0.45) | ALDH1A1KDM4EL3MBTL1GAATDP1 | |
| SCHEMBL13637013 | 0.68 | RAB9A (0.36) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072746-A1 | Inhibitors of monocarboxylate transport | ASTRAZENECA AB (SE) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072746-A1 | Inhibitors of monocarboxylate transport | SLC16A1, SLC16A7, SLC16A3 | ALDH1A1 788/4885KDM4E 1317/4885L3MBTL1 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.