Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5604568

C[n+]1cccc(-c2ccccc2)c1.[Cl-]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.58
SLC22A1 O15245 1/20 0.58
SLC22A3 O75751 1/20 0.58
SLC6A4 P31645 1/20 0.58
LMNA P02545 2/20 0.48
HDAC8 Q9BY41 6/20 0.48
TERT O14746 1/20 0.45
APOBEC3A P31941 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
NNMT P40261 1/20 0.41
USP2 O75604 1/20 0.41
KDM4E B2RXH2 1/20 0.39
NOTUM Q6P988 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10256554 0.98 SLC22A2 (0.61) SLC22A2SLC22A1SLC22A3SLC6A4LMNA
SCHEMBL16711558 0.90 HDAC8 (0.56) SLC22A2SLC22A1SLC22A3SLC6A4LMNA
SCHEMBL10680169 0.86 SLC22A2 (0.65) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8
SCHEMBL12849572 0.78 NNMT (0.49) APOBEC3AAPOBEC3GSMN1; SMN2NNMTUSP2
Hydrochloric Acid SCHEMBL163494 0.77 SLC22A2 (0.94) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8
SCHEMBL20524229 0.74 TERT (0.47) SLC22A2SLC22A1SLC22A3SLC6A4LMNA
SCHEMBL5143707 0.74 HDAC8 (0.42) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8
SCHEMBL37321 0.74 SLC22A2 (1.00) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8
Hydrochloric Acid SCHEMBL28806114 0.74 SLC22A2 (0.62) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8
SCHEMBL8827505 0.74 SLC22A2 (1.00) SLC22A2SLC22A1SLC22A3SLC6A4HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270602-B1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU KOSAN CO (JP) 2007-10-03 EP disclosed
US-7176266-B2 Catalyst for vinyl compound polymerization and process for producing vinyl polymer IDEMITSU KOSAN CO. LTD. (JP) 2007-02-13 US disclosed
US-6835788-B2 As polymerization catalyst IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
US-20040259720-A1 Catalyst for vinyl compound polymerization and process for producing vinyl polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-23 US disclosed
US-20030027716-A1 Catalyst for vinyl compounds and process for production of vinyl polymers IDEMITSU KOSAN CO. LTD. (JP) 2003-02-06 US disclosed
EP-1270602-A1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1136122-A1 TRANSITION METAL CATALYSTS AND PROCESSES FOR PRODUCING $g(a)-OLEFIN AND VINYL COMPOUND POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-09-26 EP disclosed