SCHEMBL5604928

SCHEMBL5604928

CNC(=O)c1ccc(C(=O)NC)c(N=O)c1N=O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.45
▸ HDAC2 Q92769 1/20 0.45
▸ HDAC8 Q9BY41 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45
▸ PLK1 P53350 8/20 0.42
▸ HPGD P15428 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ NEU3 Q9UQ49 1/20 0.41
▸ MAPK10 P53779 1/20 0.39
▸ CA2 P00918 1/20 0.38
▸ MMP13 P45452 1/20 0.37
▸ BRD4 O60885 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ EPHX2 P34913 1/20 0.36
▸ NR1H4 Q96RI1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30951645 1.00 GAA (0.45) GAAHDAC2HDAC8HDAC6PLK1
SCHEMBL10156467 0.72 NEU3 (0.42) GAAHDAC2HDAC8HDAC6PLK1
SCHEMBL30997032 0.72 NEU3 (0.56) GAAHDAC2HDAC8HDAC6PLK1
SCHEMBL17340272 0.71 MAPT (0.42) GAAHPGDSMN1; SMN2NEU3POLB
SCHEMBL13607305 0.71 HDAC8 (0.59) HDAC2HDAC8HDAC6PLK1HPGD
SCHEMBL20740635 0.70 CYP1A2 (0.52) GAAHDAC8HPGDTSHRHTT
SCHEMBL2344909 0.70 GAA (0.71) GAAHDAC2HDAC8HDAC6PLK1
SCHEMBL13520263 0.70 PLK1 (0.72) GAAHDAC8PLK1HPGDMAPK10
SCHEMBL20900607 0.69 GAA (0.50) GAAHDAC2HDAC8HDAC6PLK1
SCHEMBL250247 0.69 HDAC6 (0.80) GAAHDAC2HDAC8HDAC6PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522876-B1 Method of making silicone rubber films SHINETSU CHEMICAL CO (JP) 1998-12-09 — — EP claimed
US-5482978-A Expandable conductive silicone rubber composition and conductive sponge roll SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-01-09 — — US claimed
CN-110372966-B Sound-insulation heat-preservation rubber product and preparation method thereof 南京大毛牛环保科技有限公司 2022-03-01 — — CN disclosed
US-10128131-B2 Sealing sheet with separators on both surfaces, and method for manufacturing semiconductor device NITTO DENKO CORPORATION (JP) 2018-11-13 — — US disclosed
US-20170040287-A1 ELECTRONIC COMPONENT DEVICE PRODUCTION METHOD AND ELECTRONIC COMPONENT SEALING SHEET NITTO DENKO CORPORATION (JP) 2017-02-09 — — US disclosed
US-20160300733-A1 SEALING SHEET WITH SEPARATORS ON BOTH SURFACES, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE NITTO DENKO CORPORATION (JP) 2016-10-13 — — US disclosed
EP-0790279-B2 Liquid crystal polyester resin composition SUMITOMO CHEMICAL CO (JP) 2007-07-18 — — EP disclosed
EP-0790279-B1 Liquid crystal polyester resin composition SUMITOMO CHEMICAL CO (JP) 2002-05-15 — — EP disclosed
US-6329465-B1 TRANSPARENCY, MECHANICAL STRENGTH AND MOLDABILITY MITSUI CHEMICAL INC (JP) 2001-12-11 — — US disclosed
EP-1086963-A1 USE OF ETHYLENE/$g(a)-OLEFIN COPOLYMER AND USE OF ETHYLENE COPOLYMER COMPOSITION Mitsui Chemicals, Inc. (JP) 2001-03-28 — — EP disclosed
EP-0982362-A1 ETHYLENE COPOLYMER COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2000-03-01 — — EP disclosed
EP-0790279-A2 Liquid crystal polyester resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-20 — — EP disclosed
EP-0183148-B1 PROCESS FOR PREPARING A SILICONE FOAM BAYER AG (DE) 1989-08-23 — — EP disclosed
US-4704408-A Process for the manufacture of a silicone foam BAYER AKTIENGESELLSCHAFT (DE) 1987-11-03 — — US disclosed
US-4663266-A Thermal development of photosensitive materials employing microencapsulated radiation sensitive compositions THE MEAD CORPORATION (US) 1987-05-05 — — US disclosed
US-4640150-A Steering wheel with integrally-skinned foamed thermoplastic resin-covered handwheel core having flow mark-obscuring abrasion-resistant coating TOYODA GOSEI CO., LTD. (JP) 1987-02-03 — — US disclosed
US-4026844-A PLATINUM CATALYST, ORGANO-HYDROGEN SILOXANE COMPOUNDS DOW CORNING CORPORATION (US) 1977-05-31 — — US disclosed
US-4026843-A ORGANO-HYDROGEN SILOXANE COMPOUNDS, ALCOHOLS, AND PLATINUM CATALYST DOW CORNING CORPORATION (US) 1977-05-31 — — US disclosed
US-4024091-A FLAME RETARDANT DOW CORNING CORPORATION (US) 1977-05-17 — — US disclosed
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