Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376702 | 1.00 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL1884341 | 1.00 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL27547071 | 0.98 | GAA (0.70) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL10054998 | 0.95 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL673127 | 0.91 | ALDH1A1 (0.67) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL11010837 | 0.88 | GAA (0.59) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL11207120 | 0.87 | ALDH1A1 (0.65) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL3408275 | 0.87 | ALDH1A1 (0.65) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL8090683 | 0.87 | GAA (0.63) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL19018126 | 0.87 | ALDH1A1 (0.67) | GAAALDH1A1KDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57209908-A | — | — | None | — | — | JP | disclosed |
| JP-56167708-A | — | — | None | — | — | JP | disclosed |
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| US-20170008863-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | CHONG, HYUN-SOON, PHD | 2017-01-12 | — | — | US | disclosed |
| US-9446995-B2 | Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| EP-2173713-B1 | Piperidinyl derivatives as modulators of chemokine receptor activity | BRISTOL MYERS SQUIBB CO (US) | 2016-02-17 | — | — | EP | disclosed |
| US-9067955-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon—carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-30 | — | — | US | disclosed |
| CN-102659832-B | Preparation method of tetracyclic terpene compound | CHINESE ACAD INST CHEMISTRY | 2014-11-26 | — | — | CN | disclosed |
| EP-2623509-A1 | Method of producing an optically active amine compound by catalytic asymmetric hydrogenation using a ruthenium-diphosphine complex | Kanto Kagaku Kabushiki Kaisha (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-8501782-B2 | Piperidinyl derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-06 | — | — | US | disclosed |
| EP-0068290-B1 | OPTICALLY ACTIVE POLYMERS OF METHACRYLATE ESTERS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-01-16 | — | — | EP | disclosed |
| EP-0034337-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4478953-A | COORDINATION, POLYMERIZATION CATALYST CONTAINING A LIGAND; ORGANOMETALLIC COMPOUND AND SECONDARY AMINE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| US-4473690-A | FOR OPTICAL RESOLUTIONS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| EP-0089530-A2 | Polimerization process of optically active polymer and catalyst therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-09-28 | — | — | EP | disclosed |
| US-4375495-A | TRIPHENYLMETHYL METHACRYLATE, HELICES | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-01 | — | — | US | disclosed |
| EP-0068290-A1 | Optically active polymers of methacrylate esters | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-05 | — | — | EP | disclosed |
| JP-S57209908-A | ORGANIC POLYMER | DAICEL CHEM IND LTD | 1982-12-23 | — | — | JP | disclosed |
| JP-S56167708-A | OPTICALLY ACTIVE POLYMER | DAICEL CHEM IND LTD | 1981-12-23 | — | — | JP | disclosed |
| EP-0034337-A2 | A process for the optical resolution of a racemic mixture | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1981-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008863-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | AZI2, ABL1, DHPS | GAA 398/4885ALDH1A1 1847/4885KDM4E 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.