Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604987 | 1.00 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL1884341 | 1.00 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL27547071 | 0.98 | GAA (0.70) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL10054998 | 0.95 | GAA (0.73) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL673127 | 0.91 | ALDH1A1 (0.67) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL11010837 | 0.88 | GAA (0.59) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL11207120 | 0.87 | ALDH1A1 (0.65) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL3408275 | 0.87 | ALDH1A1 (0.65) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL8090683 | 0.87 | GAA (0.63) | GAAALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL19018126 | 0.87 | ALDH1A1 (0.67) | GAAALDH1A1KDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4375495-A | TRIPHENYLMETHYL METHACRYLATE, HELICES | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-01 | — | — | US | claimed |
| EP-0034337-A2 | A process for the optical resolution of a racemic mixture | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1981-08-26 | — | — | EP | claimed |
| EP-2623509-A1 | Method of producing an optically active amine compound by catalytic asymmetric hydrogenation using a ruthenium-diphosphine complex | Kanto Kagaku Kabushiki Kaisha (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2013-08-01 | — | — | US | disclosed |
| WO-2009019469-A2 | PYRROLIDINES AS CATALYST COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2009-02-12 | — | — | WO | disclosed |
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
| US-4555574-A | MAIN UNIT OF POLYMER USEFUL AS SEPARATING AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-11-26 | — | — | US | disclosed |
| US-4511475-A | RESOLUTION OF RACEMIC MIXTURES WITH TRIPHENYLMETHYL METHACRYLATE POLYMER | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| EP-0068290-B1 | OPTICALLY ACTIVE POLYMERS OF METHACRYLATE ESTERS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-01-16 | — | — | EP | disclosed |
| EP-0034337-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4473690-A | FOR OPTICAL RESOLUTIONS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| EP-0093511-A1 | Method for producing and optically active 2,2-dimethylcyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-09 | — | — | EP | disclosed |
| US-4375495-A | TRIPHENYLMETHYL METHACRYLATE, HELICES | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-01 | — | — | US | disclosed |
| EP-0068290-A1 | Optically active polymers of methacrylate esters | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-05 | — | — | EP | disclosed |
| EP-0034337-A2 | A process for the optical resolution of a racemic mixture | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1981-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | GAA 447/4885ALDH1A1 3445/4885KDM4E 3430/4885 |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | HRH3, TDO2, SRM | GAA 4322/4885ALDH1A1 3607/4885KDM4E 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.