Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447006 | 0.89 | SLC2A1 (0.60) | SLC2A1KMT2AMEN1ATMBCHE | |
| SCHEMBL5595495 | 0.84 | CYP3A4 (0.55) | SMN1; SMN2 | |
| SCHEMBL2443705 | 0.78 | DPP7 (0.57) | SMN1; SMN2 | |
| SCHEMBL5595494 | 0.75 | KDM4E (0.58) | KDM4E | |
| SCHEMBL14860185 | 0.75 | MAPK1 (0.63) | KMT2AMEN1KDM4ELMNAHTT | |
| SCHEMBL8315122 | 0.74 | ALDH1A1 (0.62) | KMT2AMEN1LMNAHTT | |
| SCHEMBL2444736 | 0.73 | DPP7 (0.69) | KMT2AMEN1 | |
| SCHEMBL5604920 | 0.73 | SLC6A4 (0.64) | NPY1R | |
| SCHEMBL10702781 | 0.72 | SLC2A1 (0.69) | SLC2A1KMT2AMEN1ATMBCHE | |
| SCHEMBL31241513 | 0.72 | CHRM2 (0.52) | KMT2AMEN1BCHEKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809288-A1 | USE OF 1,4-BIS (3-AMINOALKYL) PIPERAZINE DERIVATIVES IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006051489-A1 | USE OF 1,4-BIS (3-AMINOALKYL) PIPERAZINE DERIVATIVES IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-05-18 | — | — | WO | disclosed |