Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 4/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecylamine SCHEMBL18953081 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Tetradecylamine SCHEMBL17107092 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL5605173 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28171575 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hexadecylamine SCHEMBL17107095 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3526719 | 0.97 | DNM1 (0.60) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octadecylamine SCHEMBL27827461 | 0.93 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Tetradecylamine SCHEMBL6552384 | 0.92 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL466461 | 0.92 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL11297635 | 0.92 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160937-B2 | Flame retardant aromatic polycarbonate resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20050154103-A1 | Blend with organic acid, sulfonic acid ester, or monomeric acid anhydride; alkali or alkaline earth metal salt carboxylate; and fluoropolymer; melt stability; heat, impact and aging resistance; waterproofing; injection and extrusion molding | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-07-14 | — | — | US | disclosed |