SCHEMBL740098

SCHEMBL740098

Cc1c(N)c(C(C)C)cc(C(C)C)c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 3/20 0.34
TRPA1 O75762 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABRA1 P14867 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10536002 0.87 ALDH1A1 (0.40) POLBGAAGFERCA1CA2
SCHEMBL341228 0.78 CA1 (0.35) POLBGAAGFERCA1CA2
SCHEMBL2735032 0.78 NOS2 (0.43) POLBGAAGFERCA1CA2
SCHEMBL19998489 0.76 LMNA (0.38) POLBGAAGFERCA1CA2
SCHEMBL560581 0.75 TSHR (0.39) GAAALDH1A1TSHR
SCHEMBL24891613 0.74
SCHEMBL2155116 0.74 ALDH1A1 (0.38) POLBGAAGFERCA1CA2
SCHEMBL461449 0.74 CA1 (0.55) POLBGAAGFERCA1CA2
SCHEMBL165193 0.74 ALDH1A1 (0.36) POLBGAAGFERLMNAALDH1A1
SCHEMBL19197818 0.74 CA1 (0.32) POLBGAAGFERCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-03-10 US disclosed
EP-3922656-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL AND USE OF SAME MITSUI CHEMICALS INC (JP) 2026-01-14 EP disclosed
WO-2025106171-A1 MULTILAYER COMPOSITE ARTICLES CONTAINING REINFORCED POLYURETHANE ELASTOMER SKINS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-22 WO disclosed
CN-113474389-B Polymerizable composition for optical material, and use thereof 三井化学株式会社 2024-05-24 CN disclosed
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US disclosed
US-11447657-B2 Compositions including alpha-alumina particles and methods of their use 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-09-20 US disclosed
US-20220289945-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2022-09-15 US disclosed
EP-1250370-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
EP-1250369-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
WO-2002022309-A1 POLISHING PAD COMPRISING PARTICULATE POLYMER AND CROSSLINKED POLYMER BINDER PPG INDUSTRIES OHIO, INC. (US) 2002-03-21 WO disclosed
US-20010050356-A1 Photochromic organic resin composition TRANSITIONS OPTICAL LIMITED (IE) 2001-12-13 US disclosed
WO-2001036506-A1 OPTICAL RESIN COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036507-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036508-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
US-4611045-A POLYURETHANES MODIFIED WITH CHAIN EXTENDERS ETHYL CORPORATION (US) 1986-09-09 US disclosed
US-4440952-A POLYURETHANE CHAIN EXTENDER ETHYL CORPORATION (US) 1984-04-03 US disclosed
US-4423200-A FROM POLYURETHANE AND CHAIN EXTENDING AROMATIC DIAMINE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same VCL, LBR, ACR POLB 2303/4885GAA 2338/4885GFER 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.