SCHEMBL5605849

SCHEMBL5605849

Cc1ccc(P(=O)(O)c2ccccc2)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.44
CFTR P13569 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
ACP3 P15309 1/20 0.40
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
NFE2L2 Q16236 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15565247 0.86 TSHR (0.48) LMNATSHRHTTCFTRCA2
SCHEMBL25797392 0.85 HPGD (0.48) HTTCFTRCA2CA4CA5A
SCHEMBL497565 0.85 LMNA (0.48) LMNATSHRHTTACP3KMT2A
SCHEMBL30598263 0.81 CA2 (0.48) LMNATSHRHTTCFTRCA2
SCHEMBL2473967 0.81 CA2 (0.48) LMNATSHRHTTCFTRCA2
SCHEMBL15717372 0.78 TSHR (0.47) LMNATSHRHTTCFTRCA2
SCHEMBL30155025 0.77 CYP1A2 (0.51) LMNATSHRHTTACP3KMT2A
SCHEMBL563887 0.77 CYP1A2 (0.51) LMNATSHRHTTACP3KMT2A
SCHEMBL5605189 0.77 TSHR (0.82) LMNATSHRHTTCFTRCA2
SCHEMBL23658870 0.76 ALDH1A1 (0.41) LMNAHTTKDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670860-B1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORP (US) 2007-04-04 EP disclosed
US-20050075024-A1 Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability ALBEMARLE CORPORATION 2005-04-07 US disclosed