Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TYR | P14679 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675039 | 1.00 | ALOX5 (0.52) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL23880370 | 0.98 | ALOX5 (0.48) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL12925073 | 0.91 | ALOX5 (0.47) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL725139 | 0.91 | ALOX5 (0.47) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL17767410 | 0.88 | ALOX5 (0.43) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL21286971 | 0.86 | TYR (0.45) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL11983254 | 0.84 | THRA (0.42) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL3657714 | 0.81 | ALOX5 (0.44) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL5684607 | 0.81 | TYR (0.53) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL28209900 | 0.80 | ESR1 (0.53) | ALOX5CYP3A4TYRTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302387-B | Metal organic framework with exceptionally large pore openings | 加利福尼亚大学董事会 | 2019-06-18 | — | — | CN | disclosed |
| EP-2766046-B1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNIV CALIFORNIA (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9669098-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669098-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669098-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-9078922-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-9078922-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-8658751-B2 | Molecule-based magnetic polymers and methods | THE UNIVERSITY OF AKRON (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658751-B2 | Molecule-based magnetic polymers and methods | THE UNIVERSITY OF AKRON (US) | 2014-02-25 | — | — | US | disclosed |
| WO-2013112212-A2 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-01 | — | — | WO | disclosed |
| US-20130122297-A1 | MOLECULAR GAUGE BLOCKS FOR BUILDING ON THE NANOSCALE | NORTHWESTERN UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | US | disclosed |
| US-20120035330-A1 | MOLECULE-BASED MAGNETIC POLYMERS AND METHODS | THE UNIVERSITY OF AKRON | 2012-02-09 | — | — | US | disclosed |
| US-20120035330-A1 | MOLECULE-BASED MAGNETIC POLYMERS AND METHODS | THE UNIVERSITY OF AKRON | 2012-02-09 | — | — | US | disclosed |
| US-7718760-B2 | π-Conjugated polymer and manufacturing method thereof | RICOH COMPANY, LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | ALOX5 1076/4885CYP3A4 1680/4885TYR 1373/4885 |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | ALOX5 1076/4885CYP3A4 1680/4885TYR 1373/4885 |
| US-20130122297-A1 | MOLECULAR GAUGE BLOCKS FOR BUILDING ON THE NANOSCALE | POF1B, PCNA, OGG1 | ALOX5 1523/4885CYP3A4 4119/4885TYR 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.