Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597057 | 0.80 | HPGD (0.54) | TAAR1LMNAMEN1MAPTHPGD | |
| SCHEMBL5596291 | 0.75 | OGA (0.51) | L3MBTL1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL5543319 | 0.74 | TAAR1 (0.53) | TAAR1RXFP1LMNAMEN1ALDH1A1 | |
| SCHEMBL5596251 | 0.72 | HPGD (0.45) | TAAR1MEN1HPGDKMT2AHDAC3 | |
| SCHEMBL27537248 | 0.72 | GFER (0.38) | HPGDHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL7014068 | 0.71 | HTR7 (0.51) | RXFP1LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL5596807 | 0.71 | LMNA (0.59) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL27770501 | 0.70 | TAAR1 (0.62) | TAAR1LMNAMEN1MAPTKMT2A | |
| SCHEMBL15432467 | 0.69 | TAAR1 (0.57) | TAAR1LMNAMEN1MAPTHTT | |
| SCHEMBL5596745 | 0.69 | POLB (0.45) | RXFP1LMNAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |