Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469076 | 0.91 | PTPN1 (0.46) | PPARGPPARDPPARAAKR1B10AKR1B1 | |
| SCHEMBL28275335 | 0.90 | CA1 (0.45) | AKR1B10AKR1B1CA1CA2CA4 | |
| SCHEMBL5463214 | 0.87 | AKR1B1 (0.46) | AKR1B10AKR1B1CA1CA2CA4 | |
| SCHEMBL15419981 | 0.83 | NFKB1 (0.50) | AKR1B10AKR1B1CA1CA2CA4 | |
| SCHEMBL26046329 | 0.83 | CA1 (0.46) | CA1CA2CA4NFKB1GAA | |
| SCHEMBL1405663 | 0.83 | KDM4E (0.46) | CA1CA2CA4NFKB1GAA | |
| SCHEMBL29065702 | 0.83 | NFKB1 (0.50) | AKR1B10AKR1B1CA1CA2CA4 | |
| Phenol SCHEMBL28872804 | 0.83 | CA1 (0.44) | CA1CA2CA4NFKB1PTGER4 | |
| SCHEMBL2931781 | 0.83 | ESR1 (0.47) | CA1CA2CA4NFKB1PTGER4 | |
| SCHEMBL28238937 | 0.82 | CA1 (0.45) | CA1CA2CA4NFKB1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109828052-A | A kind of quick identification Rhizoma Et Radix Notopterygii type, the true and false or whether there is or not method | 西南民族大学 | 2019-05-31 | — | — | CN | claimed |
| US-20070042026-A1 | Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions | MORNINGSIDE VENTURE INVESTMENTS LIMITED | 2007-02-22 | — | — | US | claimed |
| CN-109248265-A | Traditional Chinese medicine composition for treating breast cancer | 浏阳市利美免疫力修复中心有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-109248266-A | Traditional Chinese medicine composition for treating lymphoma | 浏阳市利美免疫力修复中心有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-108315140-A | A kind of preparation method for the green and healthy pure grain wine promoting physical efficiency, strengthen immunity | 广州市众颐康酒业有限公司 | 2018-07-24 | — | — | CN | disclosed |
| CN-105944070-A | Medicine preparation for treating intensive care respiratory system infection and preparation method thereof | 姚鲁肃 | 2016-09-21 | — | — | CN | disclosed |
| CN-102727761-B | Medicine for treating alopecia seborrheica and preventing hair drying and bifurcating and method for preparing medicine | ZHENGZHOU ZHANGGUANG101 HAIR GROWING TECHNOLOGY CO LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-102727761-A | Medicine for treating alopecia seborrheica and preventing hair drying and bifurcating and method for preparing medicine | ZHENGZHOU ZHANGGUANG101 HAIR GROWING TECHNOLOGY CO LTD | 2012-10-17 | — | — | CN | disclosed |
| US-20070042026-A1 | Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions | MORNINGSIDE VENTURE INVESTMENTS LIMITED | 2007-02-22 | — | — | US | disclosed |