Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065702 | 1.00 | NFKB1 (0.50) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5464966 | 0.90 | MIF (0.44) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28276592 | 0.87 | CA1 (0.51) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5470601 | 0.86 | LCK (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL10339405 | 0.86 | LCK (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5606507 | 0.83 | PPARG (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL26046327 | 0.83 | CA1 (0.49) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28249242 | 0.82 | ESR1 (0.49) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28208040 | 0.81 | ALOX5 (0.51) | NFKB1ALOX5MAOBESR1ALDH1A1 | |
| SCHEMBL6678566 | 0.78 | ESR1 (0.48) | NFKB1CA1CA2CA4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111603396-B | Poly natural polyphenol type sunscreen gel and preparation method thereof | 四川大学 | 2021-07-20 | — | — | CN | claimed |
| CN-117651544-A | Synergistic effect of dicaffeoylquinic acid and tocopherol | 西姆莱斯有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-113473964-B | Propolis liquid extract, preparation and use thereof | 阿皮奥迪科斯技术有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115671049-A | S/O/W triple nano emulsion for targeted delivery of caffeic acid phenethyl ester and preparation method and application thereof | 西华大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113455504-B | Chitosan-loaded caffeic acid ester nano-medicament and preparation method and application thereof | 江苏科技大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-113317312-B | Diluent preparation capable of prolonging normal-temperature survival period of boar semen | 福建农林大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-105586326-B | Esterase and application thereof | 江南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-111849872-B | Method for improving in-vitro fertilization effect of thawed pig sperms for non-treatment infertility | 吉林省农业科学院 | 2022-01-11 | — | — | CN | disclosed |
| CN-113455504-A | Chitosan-loaded caffeic acid ester nano-medicament and preparation method and application thereof | 江苏科技大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-113317312-A | Diluent preparation capable of prolonging normal-temperature survival period of boar semen | 福建农林大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-111849872-A | Method for improving in-vitro fertilization effect of thawed pig sperms | 吉林省农业科学院 | 2020-10-30 | — | — | CN | disclosed |
| CN-107821455-B | Traditional Chinese medicine preparation for health care and quality improvement of tobacco and use method thereof | 湖南农业大学 | 2020-09-18 | — | — | CN | disclosed |
| CN-111603396-A | Poly natural polyphenol type sunscreen gel and preparation method thereof | 四川大学 | 2020-09-01 | — | — | CN | disclosed |
| CN-111094581-A | Methods of treating liver disease | 4阵营疗法公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-111012772-A | Application of caffeic acid phenethyl ester in treating aortic valve calcification disease | 华中科技大学同济医学院附属协和医院 | 2020-04-17 | — | — | CN | disclosed |
| CN-106167795-B | Esterase and application thereof | 江南大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-110563747-A | anti-HIV compounds and crystalline forms thereof | 吉利德科学公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-106399274-B | Esterase and application thereof | 江南大学 | 2019-12-10 | — | — | CN | disclosed |
| CN-106434598-B | Esterase and application thereof | 江南大学 | 2019-12-06 | — | — | CN | disclosed |
| US-20140023721-A1 | METHOD OF EXTRACTING ACTIVE MOLECULES FROM NATURAL RESINS AND USE THEREOF | RODE PHARMA S.R.L. (IT) | 2014-01-23 | — | — | US | disclosed |