Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15419981 | 1.00 | NFKB1 (0.50) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5464966 | 0.90 | MIF (0.44) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28276592 | 0.87 | CA1 (0.51) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5470601 | 0.86 | LCK (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL10339405 | 0.86 | LCK (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL5606507 | 0.83 | PPARG (0.48) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL26046327 | 0.83 | CA1 (0.49) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28249242 | 0.82 | ESR1 (0.49) | NFKB1CA1CA2CA4ALOX5 | |
| SCHEMBL28208040 | 0.81 | ALOX5 (0.51) | NFKB1ALOX5MAOBESR1ALDH1A1 | |
| SCHEMBL6678566 | 0.78 | ESR1 (0.48) | NFKB1CA1CA2CA4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113473964-B | Propolis liquid extract, preparation and use thereof | 阿皮奥迪科斯技术有限公司 | 2023-06-23 | — | — | CN | disclosed |