Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | INPP5B | P32019 | 1/20 | 0.34 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606605 | 0.86 | GPR84 (0.45) | GPR84CES1L3MBTL1HPGDMAPT | |
| SCHEMBL5606866 | 0.80 | GPR84 (0.40) | GPR84SRCCES1L3MBTL1HPGD | |
| SCHEMBL8500693 | 0.77 | MAPT (0.44) | CES1L3MBTL1HPGDMAPTALDH1A1 | |
| SCHEMBL5607172 | 0.76 | MPO (0.54) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL27532472 | 0.74 | MAPT (0.46) | L3MBTL1HPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL10782148 | 0.74 | CES1 (0.41) | GPR84CES1L3MBTL1HPGDACP3 | |
| SCHEMBL19096363 | 0.74 | CES1 (0.41) | GPR84CES1L3MBTL1HPGDMAPT | |
| SCHEMBL13160775 | 0.73 | MAPT (0.35) | CES1L3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL6161470 | 0.73 | CES1 (0.39) | CES1L3MBTL1HPGDMAPTCYP2A6 | |
| SCHEMBL27677730 | 0.72 | CES1 (0.39) | GPR84CES1L3MBTL1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005528450-A | — | — | 2005-09-22 | — | — | JP | claimed |
| EP-1509484-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP Assets B.V. (NL) | 2005-03-02 | — | — | EP | claimed |
| WO-2003102202-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2003-12-11 | — | — | WO | claimed |
| US-6608212-B1 | Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene | PFIZER, INC. | 2003-08-19 | — | — | US | claimed |
| EP-1754709-A1 | Process for preparing vinylphosphates | DSM IP Assets B.V. (NL) | 2007-02-21 | — | — | EP | disclosed |
| EP-1509484-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP Assets B.V. (NL) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003102202-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2003-12-11 | — | — | WO | disclosed |
| US-6608212-B1 | Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene | PFIZER, INC. | 2003-08-19 | — | — | US | disclosed |