Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825946 | 0.89 | L3MBTL1 (0.42) | CES1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29446604 | 0.79 | CES1 (0.35) | CES1MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8772548 | 0.79 | CES1 (0.35) | CES1MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL28323714 | 0.79 | CES1 (0.35) | CES1MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6909323 | 0.79 | CDC25A (0.38) | MAPTRAB9ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL19096363 | 0.77 | CES1 (0.41) | CES1MAPTL3MBTL1MEN1PLA2G1B | |
| SCHEMBL8500693 | 0.77 | MAPT (0.44) | CES1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5606605 | 0.76 | GPR84 (0.45) | CES1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27677730 | 0.76 | CES1 (0.39) | CES1MAPTL3MBTL1HPGDG6PC1 | |
| SCHEMBL5606609 | 0.73 | GPR84 (0.43) | CES1MAPTRAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928599-B1 | LEWIS ACID CATALYZED HALOGENATION OF ACTIVATED CARBON ATOMS | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-10-03 | — | — | EP | disclosed |
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5254731-A | Enzyme inhibitors; leukotriene disorders | GRUENENTHAL GMBH (DE) | 1993-10-19 | — | — | US | disclosed |