SCHEMBL5606645

SCHEMBL5606645

OC1(O)C=CC(c2ccccc2)=CC1(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15090810 0.77 ALDH1A1 (0.31) HDAC1HDAC2
SCHEMBL8221198 0.76 MEN1 (0.31) MEN1NPC1RAB9AKMT2A
SCHEMBL27740587 0.76
SCHEMBL15062380 0.76 MEN1 (0.30) MEN1KMT2A
SCHEMBL14322367 0.73 HDAC1 (0.33) HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL8509907 0.72 HDAC1 (0.33) HDAC1HDAC2
SCHEMBL28603466 0.72 HDAC1 (0.33) HDAC1HDAC2MEN1NPC1RAB9A
SCHEMBL27633772 0.70 THRB (0.34)
SCHEMBL9804884 0.70 MAOA (0.35)
SCHEMBL20702294 0.69 THRB (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2117916-A None JP disclosed
CN-104918966-B Actinic-radiation curable composition, solidfied material and optical lens, optical lens piece or the film using the solidfied material used for optical part 三洋化成工业株式会社 2018-01-23 CN disclosed
US-7186766-B2 Polyacetal resin composition and process for producing the same POLYPLASTICS CO., LTD. (JP) 2007-03-06 US disclosed
US-6753363-B1 BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY POLYPLASTICS CO., LTD. (JP) 2004-06-22 US disclosed
US-20040010064-A1 Polyacetal resin composition and process for producing the same POLYPLASTICS CO., LTD. (JP) 2004-01-15 US disclosed
JP-H02117916-A THERMOTROPIC LIQUID CRYSTALLINE AROMATIC POLYESTER HIMONT IT SRL 1990-05-02 JP disclosed
EP-0343606-A1 An engineering plastic composition and an article made of the same SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed