Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5606944

CCc1cc(C)cc(CC)c1.N.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.42
PGK2 P07205 1/20 0.42
PTGS2 P35354 2/20 0.39
TP53 P04637 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
NOS3 P29474 2/20 0.36
NOS2 P35228 2/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
TRPA1 O75762 1/20 0.35
ALOX5 P09917 1/20 0.34
PTGS1 P23219 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
CNR2 P34972 1/20 0.33
OPRM1 P35372 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490825 0.97 PGK1 (0.44) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL168174 0.97 PGK1 (0.44) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL271754 0.90 ALDH1A1 (0.42) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL22905323 0.88 PGK1 (0.39) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL24709410 0.84 PGK1 (0.37) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL11802721 0.84 FFAR4 (0.41) PGK1PGK2PTGS2RAPGEF4NOS3
SCHEMBL13981840 0.84 PGK1 (0.37) PGK1PGK2PTGS2RAPGEF4NOS3
SCHEMBL16952582 0.84 PGK1 (0.41) PGK1PGK2PTGS2RAPGEF4RXRA
SCHEMBL10823008 0.84 PGK1 (0.37) PGK1PGK2PTGS2TP53RAPGEF4
SCHEMBL28806252 0.83 PTGS2 (0.48) PTGS2TP53NOS3NOS2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117599231-A Bio-based polyurethane elastomer surgical suture material and preparation method thereof 合肥工业大学 2024-02-27 CN claimed
CN-116970143-A Surgical suture, preparation method thereof and polyurethane elastomer 合肥工业大学 2023-10-31 CN claimed
CN-116218200-A Polyurethane composition and chemical mechanical polishing pad window manufactured by same 万华化学集团电子材料有限公司 2023-06-06 CN claimed
CN-113146488-B Water-grinding environment-friendly polishing wheel and manufacturing method thereof 广东伟艺抛磨材料有限公司 2022-06-17 CN claimed
CN-112794308-B Preparation method of carbon microspheres with columnar hierarchical structure 西安理工大学 2022-05-17 CN claimed
CN-112574385-B Anti-slippery low-rolling-resistance thermoplastic polyurethane elastomer and preparation method thereof 北京化工大学 2022-04-22 CN claimed
CN-113146488-A Water-grinding environment-friendly polishing wheel and manufacturing method thereof 广东伟艺抛磨材料有限公司 2021-07-23 CN claimed
CN-112795177-A Low-water-absorption polyurethane encapsulating material and preparation method thereof 天津市橡胶工业研究所有限公司 2021-05-14 CN claimed
CN-112574385-A Anti-slippery low-rolling-resistance thermoplastic polyurethane elastomer and preparation method thereof 北京化工大学 2021-03-30 CN claimed
CN-111072901-A Ultrahigh-hardness high-temperature-resistant casting polyurethane elastomer and preparation method thereof 上海鹤城高分子科技有限公司 2020-04-28 CN claimed
CN-118146477-A Thermoplastic polyurethane elastomer composition and preparation method and application thereof 万华化学集团股份有限公司 2024-06-07 CN disclosed
CN-115651594-B Rapid-curing two-component polyurethane water-swelling sealant and preparation method thereof 中国铁路设计集团有限公司 2024-04-16 CN disclosed
CN-117599231-A Bio-based polyurethane elastomer surgical suture material and preparation method thereof 合肥工业大学 2024-02-27 CN disclosed
CN-116970143-A Surgical suture, preparation method thereof and polyurethane elastomer 合肥工业大学 2023-10-31 CN disclosed
CN-109666160-B Dynamic polymer with hybrid cross-linked network 厦门天策材料科技有限公司 2023-07-14 CN disclosed
US-5451629-A Fast bonding electrically conductive composition and structures JACOBS RICHARD (US) 1995-09-19 US disclosed
WO-1994015751-A1 FLEXIBLE BONDED ABRASIVE ARTICLES, METHODS OF PRODUCTION AND USE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-07-21 WO disclosed
US-5250085-A Coupled by silane component to cured polyurethane resin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-05 US disclosed
US-4734464-A IMPROVING SOLVENT RESISTANCE M&T CHEMICALS INC. (US) 1988-03-29 US disclosed
US-4456541-A Antioxidant diamine ETHYL CORPORATION (US) 1984-06-26 US disclosed