Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 5/20 | 0.67 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.67 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.67 |
| ▸ | LTA4H | P09960 | 12/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578646 | 0.83 | HRH3 (0.90) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL7819691 | 0.81 | LTA4H (0.90) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL2213892 | 0.81 | PSMB1 (0.67) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL229697 | 0.81 | LTA4H (0.90) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL3578343 | 0.81 | PSMB1 (0.67) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL4517043 | 0.81 | PSMB1 (0.67) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL13896856 | 0.81 | PSMB1 (0.67) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL1986761 | 0.81 | PSMB1 (0.67) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL8337754 | 0.81 | HRH3 (0.70) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL2475993 | 0.81 | ESR1 (0.75) | PSMB1PSMB5PSMB2LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754709-A1 | Process for preparing vinylphosphates | DSM IP Assets B.V. (NL) | 2007-02-21 | — | — | EP | disclosed |
| EP-1509484-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP Assets B.V. (NL) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003102202-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2003-12-11 | — | — | WO | disclosed |
| US-6608212-B1 | Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene | PFIZER, INC. | 2003-08-19 | — | — | US | disclosed |