SCHEMBL5606965

SCHEMBL5606965

COC(=O)C(=Cc1ccc(O)cc1)OC

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 10/20 0.61
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
TYR P14679 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
MIF P14174 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606962 1.00 ABCG2 (0.61) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL6062518 0.93 ABCG2 (0.55) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL6062516 0.93 ABCG2 (0.55) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL11042787 0.87 ABCG2 (0.56) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL11042783 0.87 ABCG2 (0.56) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL6062522 0.85 ABCG2 (0.49) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL5607421 0.85 ABCG2 (0.61) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL11334254 0.85 ABCG2 (0.61) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL11334255 0.85 ABCG2 (0.61) ABCG2KDM4EALDH1A1CA12CA1
SCHEMBL5607425 0.85 ABCG2 (0.61) ABCG2KDM4EALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
EP-1687250-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS Takasago International Corporation (JP) 2006-08-09 EP disclosed
WO-2005051882-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids ALDH1A2, ALDH1A3, GRHPR ABCG2 3631/4885KDM4E 3298/4885ALDH1A1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.